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The medicine can lessen the efficacy of hormonal contraceptive pills, you must check with your physician upfront if you can change to non-hormonal birth control pills. Aspirin Sinus relief medications Acetaminophen (Tylenol) Non-steroidal anti-inflammatory medications (like Aleve) Sedatives for sleep Codeine and prescription narcotics Over-the-counter combination headache remedies containing caffeine (for example Anacin, Excedrin, Bayer Select) Ergotamine preparations (including Cafergot, Migergot, Ergomar, Bellergal-S, Bel-Phen-Ergot S, Phenerbel-S, Ercaf, Wigraine, and Cafatine PB) Butalbital combination anesthetics (Goody's Headache Powder, Supac, fiorinal, fioricet) The CR report took a particularly close look in a group of medicine called the triptans, which may have become the mostly prescribed drug for migraine patients, despite the fact that MDs are unclear concerning how they work (it's believed they affect what sort of nervous system handles serotonin, that is involved in pain processing). 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